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Search Results for " tyrosine kinase-in-6 "

7

Compounds

Cat No. Product Name Synonyms Targets
T79612 Tyrosine kinase-IN-6 c-Met/HGFR
Tyrosine kinase-IN-6 is a potent inhibitor of RON splice variants, demonstrating significant anticancer and antineoplastic effects [1].
T62472 BTK-IN-6
BTK-IN-6 is a potent inhibitor of Bruton's tyrosine kinase (BTK). BTK-IN-6 has shown research potential in immune diseases, cardiovascular diseases, cancer, viral infections, inflammation, metabolic/endocrine dysfunction...
T61358 AKN-028 acetate
AKN-028 acetate, a novel tyrosine kinase (TK) inhibitor, is a potent, orally active FMS-like receptor tyrosine kinase 3 (FLT3) inhibitor with an IC 50 value of 6 nM. AKN-028 acetate inhibits FLT3 autophosphorylation. AKN...
T37604 ITK inhibitor
Interleukin-2-inducible T cell kinase (ITK) is a non-receptor tyrosine kinase expressed in T cells, NKT cells and mast cells which plays a crucial role in regulating the T cell receptor (TCR), CD28, CD2, chemokine recept...
T36643 PKI-166 hydrochloride
Potent EGFR-kinase inhibitor (IC50 = 0.7 nM). Displays >3000-fold selectivity against a panel of serine/threonine kinases. Reduces metastasis and angiogenesis in a mouse model of pancreatic cancer. Antihypertensive and o...
TMIH-0065 Acalabrutinib-d4
Acalabrutinib-d4 is a deuterated compound of Acalabrutinib. Acalabrutinib has a CAS number of 1420477-60-6. Acalabrutinib, also known as ACP-196, is an orally available inhibitor of Bruton’s tyrosine kinase (BTK) with po...
T35897 ASK120067
ASK120067 is a potent and orally active inhibitor of EGFRT790M (IC50:0.3 nM) with selectivity over EGFRWT (IC50:6.0 nM). ASK120067 is a third-generation EGFR-TKI for the research of non-small cell lung cancer (NSCLC)[1]...
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